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The Missing Heritability in T1D and Potential New Targets for Prevention

Type 1 diabetes (T1D) is a T cell-mediated disease. It is strongly associated with susceptibility haplotypes within the major histocompatibility complex, but this association accounts for an estimated 50% of susceptibility. Other studies have identified as many as 50 additional susceptibility loci,...

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Detalles Bibliográficos
Autores principales: Pierce, Brian G., Eberwine, Ryan, Noble, Janelle A., Habib, Michael, Shulha, Hennady P., Weng, Zhiping, Blankenhorn, Elizabeth P., Mordes, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647582/
https://www.ncbi.nlm.nih.gov/pubmed/23691517
http://dx.doi.org/10.1155/2013/737485