Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC

BACKGROUND: Methylaminomethyl modification of uridine or 2-thiouridine (mnm5U34 or mnm5s2U34) at the wobble position of tRNAs specific for glutamate, lysine and arginine are observed in Escherichia coli and allow for specific recognition of codons ending in A or G. In the biosynthetic pathway respon...

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Detalles Bibliográficos
Autores principales: Kim, Jungwook, Almo, Steven C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648344/
https://www.ncbi.nlm.nih.gov/pubmed/23617613
http://dx.doi.org/10.1186/1472-6807-13-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648344/
https://www.ncbi.nlm.nih.gov/pubmed/23617613
http://dx.doi.org/10.1186/1472-6807-13-5

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