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Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC
BACKGROUND: Methylaminomethyl modification of uridine or 2-thiouridine (mnm5U34 or mnm5s2U34) at the wobble position of tRNAs specific for glutamate, lysine and arginine are observed in Escherichia coli and allow for specific recognition of codons ending in A or G. In the biosynthetic pathway respon...
Autores principales: | Kim, Jungwook, Almo, Steven C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648344/ https://www.ncbi.nlm.nih.gov/pubmed/23617613 http://dx.doi.org/10.1186/1472-6807-13-5 |
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