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TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice

BACKGROUND: Airway inflammation and asthma have been linked to oxidative stress and the melastatin-related transient receptor potential cation channel, member 2 (TRPM2), which can be activated by reactive oxygen species (ROS), has emerged as a potential therapeutic target for inflammatory diseases....

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Detalles Bibliográficos
Autores principales: Sumoza-Toledo, Adriana, Fleig, Andrea, Penner, Reinhold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648402/
https://www.ncbi.nlm.nih.gov/pubmed/23631390
http://dx.doi.org/10.1186/1476-9255-10-19