A monoclonal antibody against lymphocyte function-associated antigen-1 decreases HIV-1 replication by inducing the secretion of an antiviral soluble factor

BACKGROUND: Lymphocyte Function-Associated Antigen-1 (LFA-1) likely plays a role in the pathogenesis of against HIV-1 and is known to facilitate cell-to-cell transmission of the virus. A monoclonal antibody specific for LFA-1 (Cytolin®) was evaluated as a potential therapeutic in pilot studies perfo...

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Detalles Bibliográficos
Autores principales: Rychert, Jenna, Jones, Lindsay, McGrath, Graham, Bazner, Sue, Rosenberg, Eric S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648404/
https://www.ncbi.nlm.nih.gov/pubmed/23594747
http://dx.doi.org/10.1186/1743-422X-10-120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648404/
https://www.ncbi.nlm.nih.gov/pubmed/23594747
http://dx.doi.org/10.1186/1743-422X-10-120

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