The Small Molecule Triclabendazole Decreases the Intracellular Level of Cyclic AMP and Increases Resistance to Stress in Saccharomyces cerevisiae

The Ras-adenylyl cyclase-protein kinase A nutrient-sensing pathway controls metabolism, proliferation and resistance to stress in Saccharomyces cerevisiae. The genetic disruption of this pathway increases resistance to a variety of stresses. We show here that the pharmacological inhibition of this p...

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Detalles Bibliográficos
Autores principales: Lee, Yong Joo, Shi, Runhua, Witt, Stephan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648474/
https://www.ncbi.nlm.nih.gov/pubmed/23667708
http://dx.doi.org/10.1371/journal.pone.0064337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648474/
https://www.ncbi.nlm.nih.gov/pubmed/23667708
http://dx.doi.org/10.1371/journal.pone.0064337

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