VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically engineered mouse model of lung adenocarcinoma

BACKGROUND: VEGF is one of the key drivers of physiological or pathological angiogenesis hence several VEGF inhibitors are in different stages of clinical development. To further dissect the role of VEGF in different stages of tumor progression in lung tumors, we utilized Kras(G12D-LSL) GEMMs (genet...

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Detalles Bibliográficos
Autores principales: Majeti, Bharat K, Lee, Joseph H, Simmons, Brett H, Shojaei, Farbod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648493/
https://www.ncbi.nlm.nih.gov/pubmed/23627488
http://dx.doi.org/10.1186/1471-2407-13-213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648493/
https://www.ncbi.nlm.nih.gov/pubmed/23627488
http://dx.doi.org/10.1186/1471-2407-13-213

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