Rapamycin Upregulates Autophagy by Inhibiting the mTOR-ULK1 Pathway, Resulting in Reduced Podocyte Injury

The podocyte functions as a glomerular filtration barrier. Autophagy of postmitotic cells is an important protective mechanism that is essential for maintaining the homeostasis of podocytes. Exploring an in vivo rat model of passive Heymann nephritis and an in vitro model of puromycin amino nucleoti...

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Detalles Bibliográficos
Autores principales: Wu, Lingling, Feng, Zhe, Cui, Shaoyuan, Hou, Kai, Tang, Li, Zhou, Jianhui, Cai, Guangyan, Xie, Yuansheng, Hong, Quan, Fu, Bo, Chen, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648526/
https://www.ncbi.nlm.nih.gov/pubmed/23667674
http://dx.doi.org/10.1371/journal.pone.0063799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648526/
https://www.ncbi.nlm.nih.gov/pubmed/23667674
http://dx.doi.org/10.1371/journal.pone.0063799

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