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The Transient Nature of Bunyamwera Orthobunyavirus NSs Protein Expression: Effects of Increased Stability of NSs Protein on Virus Replication

The NSs proteins of bunyaviruses are the viral interferon antagonists, counteracting the host's antiviral response to infection. During high-multiplicity infection of cultured mammalian cells with Bunyamwera orthobunyavirus (BUNV), NSs is rapidly degraded after reaching peak levels of expressio...

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Detalles Bibliográficos
Autores principales: van Knippenberg, Ingeborg, Fragkoudis, Rennos, Elliott, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648540/
https://www.ncbi.nlm.nih.gov/pubmed/23667701
http://dx.doi.org/10.1371/journal.pone.0064137