Signal Transduction Pathways in the Pentameric Ligand-Gated Ion Channels

The mechanisms of allosteric action within pentameric ligand-gated ion channels (pLGICs) remain to be determined. Using crystallography, site-directed mutagenesis, and two-electrode voltage clamp measurements, we identified two functionally relevant sites in the extracellular (EC) domain of the bact...

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Detalles Bibliográficos
Autores principales: Mowrey, David, Chen, Qiang, Liang, Yuhe, Liang, Jie, Xu, Yan, Tang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648548/
https://www.ncbi.nlm.nih.gov/pubmed/23667707
http://dx.doi.org/10.1371/journal.pone.0064326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648548/
https://www.ncbi.nlm.nih.gov/pubmed/23667707
http://dx.doi.org/10.1371/journal.pone.0064326

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