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Intratracheal IL-6 Protects against Lung Inflammation in Direct, but Not Indirect, Causes of Acute Lung Injury in Mice

INTRODUCTION: Serum and bronchoalveolar fluid IL-6 are increased in patients with acute respiratory distress syndrome (ARDS) and predict prolonged mechanical ventilation and poor outcomes, although the role of intra-alveolar IL-6 in indirect lung injury is unknown. We investigated the role of endoge...

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Detalles Bibliográficos
Autores principales: Bhargava, Rhea, Janssen, William, Altmann, Christopher, Andrés-Hernando, Ana, Okamura, Kayo, Vandivier, R. William, Ahuja, Nilesh, Faubel, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648558/
https://www.ncbi.nlm.nih.gov/pubmed/23667439
http://dx.doi.org/10.1371/journal.pone.0061405