Knockdown of Regulator of Cullins-1 (ROC1) Expression Induces Bladder Cancer Cell Cycle Arrest at the G2 Phase and Senescence

Regulator of Cullins-1 (ROC1) is a key subunit in the Cullin-RING ligase (CRL) protein complex. Overexpression of ROC1 protein is associated with tumor progression and poor prognosis of non-muscle invasive bladder transitional cell carcinoma (NMIBC). This study was designed to assess the effects of...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Liu, Zhihong, Qu, Ping, Zhou, Zhengdong, Zeng, Yigang, Fan, Jie, Liu, Yong, Guo, Yifeng, Qiu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648563/
https://www.ncbi.nlm.nih.gov/pubmed/23667514
http://dx.doi.org/10.1371/journal.pone.0062734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648563/
https://www.ncbi.nlm.nih.gov/pubmed/23667514
http://dx.doi.org/10.1371/journal.pone.0062734

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