Consensus HIV-1 FSU-A Integrase Gene Variants Electroporated into Mice Induce Polyfunctional Antigen-Specific CD4+ and CD8+ T Cells

Our objective is to create gene immunogens targeted against drug-resistant HIV-1, focusing on HIV-1 enzymes as critical components in viral replication and drug resistance. Consensus-based gene vaccines are specifically fit for variable pathogens such as HIV-1 and have many advantages over viral gen...

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Detalles Bibliográficos
Autores principales: Krotova, Olga, Starodubova, Elizaveta, Petkov, Stefan, Kostic, Linda, Agapkina, Julia, Hallengärd, David, Viklund, Alecia, Latyshev, Oleg, Gelius, Eva, Dillenbeck, Tomas, Karpov, Vadim, Gottikh, Marina, Belyakov, Igor M., Lukashov, Vladimir, Isaguliants, Maria G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648577/
https://www.ncbi.nlm.nih.gov/pubmed/23667513
http://dx.doi.org/10.1371/journal.pone.0062720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648577/
https://www.ncbi.nlm.nih.gov/pubmed/23667513
http://dx.doi.org/10.1371/journal.pone.0062720

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