Dynamics of translation by single ribosomes through mRNA secondary structures

During protein synthesis, the ribosome translates nucleotide triplets in single-stranded mRNA into polypeptide sequences. Strong downstream mRNA secondary (2°) structures, which must be unfolded for translation, can slow or even halt protein synthesis. Here we employ single molecule fluorescence res...

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Detalles Bibliográficos
Autores principales: Chen, Chunlai, Zhang, Haibo, Broitman, Steven L., Reiche, Michael, Farrell, Ian, Cooperman, Barry S., Goldman, Yale E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648610/
https://www.ncbi.nlm.nih.gov/pubmed/23542154
http://dx.doi.org/10.1038/nsmb.2544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648610/
https://www.ncbi.nlm.nih.gov/pubmed/23542154
http://dx.doi.org/10.1038/nsmb.2544

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