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Dynamics of translation by single ribosomes through mRNA secondary structures
During protein synthesis, the ribosome translates nucleotide triplets in single-stranded mRNA into polypeptide sequences. Strong downstream mRNA secondary (2°) structures, which must be unfolded for translation, can slow or even halt protein synthesis. Here we employ single molecule fluorescence res...
Autores principales: | Chen, Chunlai, Zhang, Haibo, Broitman, Steven L., Reiche, Michael, Farrell, Ian, Cooperman, Barry S., Goldman, Yale E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648610/ https://www.ncbi.nlm.nih.gov/pubmed/23542154 http://dx.doi.org/10.1038/nsmb.2544 |
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