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Conformational selection of translation initiation factor 3 signals proper substrate selection

During translation, initiation factor (IF) 3 binds to the small, 30S, ribosomal subunit and regulates the fidelity with which the initiator tRNA and mRNA start codon substrates are selected into the 30S initiation complex (30S IC). The molecular mechanism through which IF3 promotes recognition and s...

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Detalles Bibliográficos
Autores principales: Elvekrog, Margaret M., Gonzalez, Ruben L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648635/
https://www.ncbi.nlm.nih.gov/pubmed/23584454
http://dx.doi.org/10.1038/nsmb.2554