Promises and pitfalls of a Pannexin1 transgenic mouse line

Gene targeting strategies have become a powerful technology for elucidating mammalian gene function. The recently generated knockout (KO)-first strategy produces a KO at the RNA processing level and also allows for the generation of conditional KO alleles by combining FLP/FRT and Cre/loxP systems, t...

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Detalles Bibliográficos
Autores principales: Hanstein, Regina, Negoro, Hiromitsu, Patel, Naman K., Charollais, Anne, Meda, Paolo, Spray, David C., Suadicani, Sylvia O., Scemes, Eliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648696/
https://www.ncbi.nlm.nih.gov/pubmed/23675350
http://dx.doi.org/10.3389/fphar.2013.00061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648696/
https://www.ncbi.nlm.nih.gov/pubmed/23675350
http://dx.doi.org/10.3389/fphar.2013.00061

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