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Hepatitis C Virus Envelope Protein E1 Binds PERK and Represses the Unfolded Protein Response
Unfolded protein response (UPR) is a cellular adaptive response which functions to reduce stress caused by misfolded proteins in the endoplasmic reticulum (ER). We and others have previously shown that infection with hepatitis C virus (HCV) or expression of the viral proteins can trigger the UPR. HC...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648774/ https://www.ncbi.nlm.nih.gov/pubmed/23667408 http://dx.doi.org/10.2174/1874357901307010037 |