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Hepatitis C Virus Envelope Protein E1 Binds PERK and Represses the Unfolded Protein Response

Unfolded protein response (UPR) is a cellular adaptive response which functions to reduce stress caused by misfolded proteins in the endoplasmic reticulum (ER). We and others have previously shown that infection with hepatitis C virus (HCV) or expression of the viral proteins can trigger the UPR. HC...

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Detalles Bibliográficos
Autores principales: Egan, Philip A, Sobkowiak, Michal, Chan, Shiu-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648774/
https://www.ncbi.nlm.nih.gov/pubmed/23667408
http://dx.doi.org/10.2174/1874357901307010037