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S-nitrosylation of ERK inhibits ERK phosphorylation and induces apoptosis

Extracellular signal-regulated kinase (ERK) belongs to the mitogen-activated protein kinases (MAPK) superfamily. Aberrant upregulation and activation of ERK cascades may often lead to tumor cell development. However, how ERK is involved in tumor progression is yet to be defined. In current study, we...

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Detalles Bibliográficos
Autores principales: Feng, Xiujing, Sun, Tingzhe, Bei, Yuncheng, Ding, Sen, Zheng, Wei, Lu, Yan, Shen, Pingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648801/
https://www.ncbi.nlm.nih.gov/pubmed/23657295
http://dx.doi.org/10.1038/srep01814