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Prominent role for T cell-derived Tumour Necrosis Factor for sustained control of Mycobacterium tuberculosis infection

Tumour Necrosis Factor (TNF) is critical for host control of M. tuberculosis, but the relative contribution of TNF from innate and adaptive immune responses during tuberculosis infection is unclear. Myeloid versus T-cell-derived TNF function in tuberculosis was investigated using cell type-specific...

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Detalles Bibliográficos
Autores principales: Allie, Nasiema, Grivennikov, Sergei I., Keeton, Roanne, Hsu, Nai-Jen, Bourigault, Marie-Laure, Court, Nathalie, Fremond, Cecile, Yeremeev, Vladimir, Shebzukhov, Yuriy, Ryffel, Bernhard, Nedospasov, Sergei A., Quesniaux, Valerie F. J., Jacobs, Muazzam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648802/
https://www.ncbi.nlm.nih.gov/pubmed/23657146
http://dx.doi.org/10.1038/srep01809