The benefits of selecting phenotype-specific variants for applications of mixed models in genomics

Applications of linear mixed models (LMMs) to problems in genomics include phenotype prediction, correction for confounding in genome-wide association studies, estimation of narrow sense heritability, and testing sets of variants (e.g., rare variants) for association. In each of these applications,...

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Detalles Bibliográficos
Autores principales: Lippert, Christoph, Quon, Gerald, Kang, Eun Yong, Kadie, Carl M., Listgarten, Jennifer, Heckerman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648840/
https://www.ncbi.nlm.nih.gov/pubmed/23657357
http://dx.doi.org/10.1038/srep01815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648840/
https://www.ncbi.nlm.nih.gov/pubmed/23657357
http://dx.doi.org/10.1038/srep01815

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