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Nanoparticle-Based Delivery of RNAi Therapeutics: Progress and Challenges

RNA interference (RNAi) is an evolutionarily conserved, endogenous process for post-transcriptional regulation of gene expression. Although RNAi therapeutics have recently progressed through the pipeline toward clinical trials, the application of these as ideal, clinical therapeutics requires the de...

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Detalles Bibliográficos
Autores principales: Zhou, Jiehua, Shum, Ka-To, Burnett, John C., Rossi, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649006/
https://www.ncbi.nlm.nih.gov/pubmed/23667320
http://dx.doi.org/10.3390/ph6010085