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New Quantitative Method to Identify NPM1 Mutations in Acute Myeloid Leukaemia

Somatic mutations in the NPM1 gene, which encodes for nucleophosmin, have been reported to be the most frequent genetic abnormalities found in acute myeloid leukaemia (AML). Their identification and quantification remain crucial for the patients' residual disease monitoring. We investigated a n...

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Detalles Bibliográficos
Autores principales: Huet, Sarah, Jallades, Laurent, Charlot, Carole, Chabane, Kaddour, Nicolini, Franck E., Michallet, Mauricette, Magaud, Jean-Pierre, Hayette, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649360/
https://www.ncbi.nlm.nih.gov/pubmed/23691328
http://dx.doi.org/10.1155/2013/756703