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Link between Cancer and Alzheimer Disease via Oxidative Stress Induced by Nitric Oxide-Dependent Mitochondrial DNA Overproliferation and Deletion

Nitric oxide- (NO-) dependent oxidative stress results in mitochondrial ultrastructural alterations and DNA damage in cases of Alzheimer disease (AD). However, little is known about these pathways in human cancers, especially during the development as well as the progression of primary brain tumors...

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Detalles Bibliográficos
Autores principales: Aliev, Gjumrakch, Obrenovich, Mark E., Tabrez, Shams, Jabir, Nasimudeen R., Reddy, V. Prakash, Li, Yi, Burnstock, Geoffrey, Cacabelos, Ramon, Kamal, Mohammad Amjad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649749/
https://www.ncbi.nlm.nih.gov/pubmed/23691268
http://dx.doi.org/10.1155/2013/962984