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The Evidence for Hypoperfusion as a Factor in Multiple Sclerosis Lesion Development

The evidence that hypoxia is a precipitating factor in causing early MS lesions includes increased protein levels of hypoxia-inducible factor-1α; presence of the D-110 hypoxia-inducible protein; increased expression of hypoxia-inducible genes in lesions as well as in adjacent normal-appearing white...

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Detalles Bibliográficos
Autor principal: Juurlink, Bernhard H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649777/
https://www.ncbi.nlm.nih.gov/pubmed/23691321
http://dx.doi.org/10.1155/2013/598093