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Negative regulation of NF-κB signaling in T lymphocytes by the ubiquitin-specific protease USP34
BACKGROUND: NF-κB is a master gene regulator involved in plethora of biological processes, including lymphocyte activation and proliferation. Reversible ubiquitinylation of key adaptors is required to convey the optimal activation of NF-κB. However the deubiquitinylases (DUBs), which catalyze the re...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649923/ https://www.ncbi.nlm.nih.gov/pubmed/23590831 http://dx.doi.org/10.1186/1478-811X-11-25 |