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Negative regulation of NF-κB signaling in T lymphocytes by the ubiquitin-specific protease USP34

BACKGROUND: NF-κB is a master gene regulator involved in plethora of biological processes, including lymphocyte activation and proliferation. Reversible ubiquitinylation of key adaptors is required to convey the optimal activation of NF-κB. However the deubiquitinylases (DUBs), which catalyze the re...

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Detalles Bibliográficos
Autores principales: Poalas, Konstantinos, Hatchi, Emeline M, Cordeiro, Nelia, Dubois, Sonia M, Leclair, Héloïse M, Leveau, Claire, Alexia, Catherine, Gavard, Julie, Vazquez, Aimé, Bidère, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649923/
https://www.ncbi.nlm.nih.gov/pubmed/23590831
http://dx.doi.org/10.1186/1478-811X-11-25