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Leishmania mexicana Infection Induces IgG to Parasite Surface Glycoinositol Phospholipids that Can Induce IL-10 in Mice and Humans

Infection with the intracellular protozoan parasite Leishmania mexicana causes chronic disease in C57BL/6 mice, in which cutaneous lesions persist for many months with high parasite burdens (10(7)–10(8) parasites). This chronic disease process requires host IL-10 and FcγRIII. When Leishmania amastig...

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Detalles Bibliográficos
Autor principal: Buxbaum, Laurence U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649955/
https://www.ncbi.nlm.nih.gov/pubmed/23675550
http://dx.doi.org/10.1371/journal.pntd.0002224