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Bile Acid Recognition by the Clostridium difficile Germinant Receptor, CspC, Is Important for Establishing Infection

Clostridium difficile spores must germinate in vivo to become actively growing bacteria in order to produce the toxins that are necessary for disease. C. difficile spores germinate in vitro in response to certain bile acids and glycine. In other sporulating bacteria, proteins embedded within the inn...

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Detalles Bibliográficos
Autores principales: Francis, Michael B., Allen, Charlotte A., Shrestha, Ritu, Sorg, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649964/
https://www.ncbi.nlm.nih.gov/pubmed/23675301
http://dx.doi.org/10.1371/journal.ppat.1003356