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NOD2-mediated Suppression of CD55 on Neutrophils Enhances C5a Generation During Polymicrobial Sepsis

Nucleotide-binding oligomerization domain (NOD) 2 is a cytosolic protein that plays a defensive role in bacterial infection by sensing peptidoglycans. C5a, which has harmful effects in sepsis, interacts with innate proteins. However, whether NOD2 regulates C5a generation during sepsis remains to be...

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Detalles Bibliográficos
Autores principales: Oh, Sae Jin, Kim, Ji Hyung, Chung, Doo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649968/
https://www.ncbi.nlm.nih.gov/pubmed/23675299
http://dx.doi.org/10.1371/journal.ppat.1003351