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Liver X Receptors Protect from Development of Prostatic Intra-Epithelial Neoplasia in Mice
LXR (Liver X Receptors) act as “sensor” proteins that regulate cholesterol uptake, storage, and efflux. LXR signaling is known to influence proliferation of different cell types including human prostatic carcinoma (PCa) cell lines. This study shows that deletion of LXR in mouse fed a high-cholestero...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649972/ https://www.ncbi.nlm.nih.gov/pubmed/23675307 http://dx.doi.org/10.1371/journal.pgen.1003483 |