Liver X Receptors Protect from Development of Prostatic Intra-Epithelial Neoplasia in Mice

LXR (Liver X Receptors) act as “sensor” proteins that regulate cholesterol uptake, storage, and efflux. LXR signaling is known to influence proliferation of different cell types including human prostatic carcinoma (PCa) cell lines. This study shows that deletion of LXR in mouse fed a high-cholestero...

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Detalles Bibliográficos
Autores principales: Pommier, Aurélien J. C., Dufour, Julie, Alves, Georges, Viennois, Emilie, De Boussac, Hugues, Trousson, Amalia, Volle, David H., Caira, Françoise, Val, Pierre, Arnaud, Philippe, Lobaccaro, Jean-Marc A., Baron, Silvère
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649972/
https://www.ncbi.nlm.nih.gov/pubmed/23675307
http://dx.doi.org/10.1371/journal.pgen.1003483

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