The Lipid Kinase Phosphatidylinositol-4 Kinase III Alpha Regulates the Phosphorylation Status of Hepatitis C Virus NS5A

The lipid kinase phosphatidylinositol 4-kinase III alpha (PI4KIIIα) is an essential host factor of hepatitis C virus (HCV) replication. PI4KIIIα catalyzes the synthesis of phosphatidylinositol 4-phosphate (PI4P) accumulating in HCV replicating cells due to enzyme activation resulting from its intera...

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Detalles Bibliográficos
Autores principales: Reiss, Simon, Harak, Christian, Romero-Brey, Inés, Radujkovic, Danijela, Klein, Rahel, Ruggieri, Alessia, Rebhan, Ilka, Bartenschlager, Ralf, Lohmann, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649985/
https://www.ncbi.nlm.nih.gov/pubmed/23675303
http://dx.doi.org/10.1371/journal.ppat.1003359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649985/
https://www.ncbi.nlm.nih.gov/pubmed/23675303
http://dx.doi.org/10.1371/journal.ppat.1003359

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