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The Lipid Kinase Phosphatidylinositol-4 Kinase III Alpha Regulates the Phosphorylation Status of Hepatitis C Virus NS5A
The lipid kinase phosphatidylinositol 4-kinase III alpha (PI4KIIIα) is an essential host factor of hepatitis C virus (HCV) replication. PI4KIIIα catalyzes the synthesis of phosphatidylinositol 4-phosphate (PI4P) accumulating in HCV replicating cells due to enzyme activation resulting from its intera...
Autores principales: | Reiss, Simon, Harak, Christian, Romero-Brey, Inés, Radujkovic, Danijela, Klein, Rahel, Ruggieri, Alessia, Rebhan, Ilka, Bartenschlager, Ralf, Lohmann, Volker |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649985/ https://www.ncbi.nlm.nih.gov/pubmed/23675303 http://dx.doi.org/10.1371/journal.ppat.1003359 |
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