Decrease of 5-Hydroxymethylcytosine Is Associated with Progression of Hepatocellular Carcinoma through Downregulation of TET1

DNA methylation is an important epigenetic modification and is frequently altered in cancer. Convert of 5-methylcytosine (5 mC) to 5-hydroxymethylcytosine (5 hmC) by ten-eleven translocation (TET) family enzymes plays important biological functions in embryonic stem cells, development, aging and dis...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Chungang, Liu, Limei, Chen, Xuejiao, Shen, Junjie, Shan, Juanjuan, Xu, Yanmin, Yang, Zhi, Wu, Lin, Xia, Feng, Bie, Ping, Cui, Youhong, Bian, Xiu-wu, Qian, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650038/
https://www.ncbi.nlm.nih.gov/pubmed/23671639
http://dx.doi.org/10.1371/journal.pone.0062828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650038/
https://www.ncbi.nlm.nih.gov/pubmed/23671639
http://dx.doi.org/10.1371/journal.pone.0062828

Ejemplares similares