γδ T Cells Acquire Effector Fates in the Thymus and Differentiate into Cytokine-Producing Effectors in a Listeria Model of Infection Independently of CD28 Costimulation

Both antigen recognition and CD28 costimulation are required for the activation of naïve αβ T cells and their subsequent differentiation into cytokine-producing or cytotoxic effectors. Notably, this two-signal paradigm holds true for all αβ T cell subsets, regardless of whether they acquire their ef...

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Detalles Bibliográficos
Autores principales: Laird, Renee M., Wolf, Benjamin J., Princiotta, Michael F., Hayes, Sandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650071/
https://www.ncbi.nlm.nih.gov/pubmed/23671671
http://dx.doi.org/10.1371/journal.pone.0063178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650071/
https://www.ncbi.nlm.nih.gov/pubmed/23671671
http://dx.doi.org/10.1371/journal.pone.0063178

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