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BAF60c drives glycolytic muscle formation and improves glucose homeostasis through Deptor-mediated AKT activation

A shift from oxidative to glycolytic metabolism has been associated with skeletal muscle insulin resistance in type 2 diabetes(1–5). However, whether this metabolic switch is deleterious or adaptive remains controversial(6–8), in part due to limited understanding of the regulatory network that direc...

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Detalles Bibliográficos
Autores principales: Meng, Zhuo-Xian, Li, Siming, Wang, Lin, Ko, Hwi Jin, Lee, Yongjin, Jung, Dae Young, Okutsu, Mitsuharu, Yan, Zhen, Kim, Jason K., Lin, Jiandie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650110/
https://www.ncbi.nlm.nih.gov/pubmed/23563706
http://dx.doi.org/10.1038/nm.3144