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BAF60c drives glycolytic muscle formation and improves glucose homeostasis through Deptor-mediated AKT activation
A shift from oxidative to glycolytic metabolism has been associated with skeletal muscle insulin resistance in type 2 diabetes(1–5). However, whether this metabolic switch is deleterious or adaptive remains controversial(6–8), in part due to limited understanding of the regulatory network that direc...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650110/ https://www.ncbi.nlm.nih.gov/pubmed/23563706 http://dx.doi.org/10.1038/nm.3144 |