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The spatial pattern of light determines the kinetics and modulates backpropagation of optogenetic action potentials

Optogenetics offers an unprecedented ability to spatially target neuronal stimulations. This study investigated via simulation, for the first time, how the spatial pattern of excitation affects the response of channelrhodopsin-2 (ChR2) expressing neurons. First we described a methodology for modelin...

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Detalles Bibliográficos
Autores principales: Grossman, Nir, Simiaki, Vasiliki, Martinet, Claire, Toumazou, Christofer, Schultz, Simon R., Nikolic, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650242/
https://www.ncbi.nlm.nih.gov/pubmed/23179855
http://dx.doi.org/10.1007/s10827-012-0431-7