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The spatial pattern of light determines the kinetics and modulates backpropagation of optogenetic action potentials
Optogenetics offers an unprecedented ability to spatially target neuronal stimulations. This study investigated via simulation, for the first time, how the spatial pattern of excitation affects the response of channelrhodopsin-2 (ChR2) expressing neurons. First we described a methodology for modelin...
Autores principales: | Grossman, Nir, Simiaki, Vasiliki, Martinet, Claire, Toumazou, Christofer, Schultz, Simon R., Nikolic, Konstantin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650242/ https://www.ncbi.nlm.nih.gov/pubmed/23179855 http://dx.doi.org/10.1007/s10827-012-0431-7 |
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