Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

MicroRNAs (miRNAs) play key roles in gene regulation, but reliable bioinformatic or experimental identification of their targets remains difficult. To provide an unbiased view of human miRNA targets, we developed a technique for ligation and sequencing of miRNA-target RNA duplexes associated with hu...

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Detalles Bibliográficos
Autores principales: Helwak, Aleksandra, Kudla, Grzegorz, Dudnakova, Tatiana, Tollervey, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650559/
https://www.ncbi.nlm.nih.gov/pubmed/23622248
http://dx.doi.org/10.1016/j.cell.2013.03.043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650559/
https://www.ncbi.nlm.nih.gov/pubmed/23622248
http://dx.doi.org/10.1016/j.cell.2013.03.043

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