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Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding
MicroRNAs (miRNAs) play key roles in gene regulation, but reliable bioinformatic or experimental identification of their targets remains difficult. To provide an unbiased view of human miRNA targets, we developed a technique for ligation and sequencing of miRNA-target RNA duplexes associated with hu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650559/ https://www.ncbi.nlm.nih.gov/pubmed/23622248 http://dx.doi.org/10.1016/j.cell.2013.03.043 |