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Differential effects of norUDCA and UDCA in obstructive cholestasis in mice
BACKGROUND & AIMS: The quest for effective drugs to treat cholangiopathies led to the development of norUDCA previously shown to have potent choleretic effects and to heal cholangiopathy in Abcb4 knockout (Abcb4(−/−)) mice. Its mother compound UDCA had detrimental effects in common bile duct lig...
Autores principales: | Fickert, Peter, Pollheimer, Marion J., Silbert, Dagmar, Moustafa, Tarek, Halilbasic, Emina, Krones, Elisabeth, Durchschein, Franziska, Thüringer, Andrea, Zollner, Gernot, Denk, Helmut, Trauner, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650580/ https://www.ncbi.nlm.nih.gov/pubmed/23369794 http://dx.doi.org/10.1016/j.jhep.2013.01.026 |
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