Microfluidic Chemotaxis Platform for Differentiating the Roles of Soluble and Bound Amyloid-β on Microglial Accumulation

Progressive microglial accumulation at amyloid-β (Aβ) plaques is a well-established signature of the pathology of Alzheimer's disease, but how and why microglia accumulate in the vicinity of Aβ plaques is unknown. To understand the distinct roles of Aβ on microglial accumulation, we quantified...

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Detalles Bibliográficos
Autores principales: Cho, Hansang, Hashimoto, Tadafumi, Wong, Elisabeth, Hori, Yukiko, Wood, Levi B., Zhao, Lingzhi, Haigis, Kevin M., Hyman, Bradley T., Irimia, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650586/
https://www.ncbi.nlm.nih.gov/pubmed/23665843
http://dx.doi.org/10.1038/srep01823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650586/
https://www.ncbi.nlm.nih.gov/pubmed/23665843
http://dx.doi.org/10.1038/srep01823

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