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Adjunctive immunotherapy with α-crystallin based DNA vaccination reduces Tuberculosis chemotherapy period in chronically infected mice

By employing modified Cornell model, we have evaluated the potential of adjunctive immunotherapy with DNA vaccines to shorten the tuberculosis chemotherapy period and reduce disease reactivation. We demonstrate that α-crystallin based DNA vaccine (DNAacr) significantly reduced the chemotherapy perio...

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Detalles Bibliográficos
Autores principales: Chauhan, Priyanka, Jain, Ruchi, Dey, Bappaditya, Tyagi, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650662/
https://www.ncbi.nlm.nih.gov/pubmed/23660989
http://dx.doi.org/10.1038/srep01821