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TERRA Expression Levels Do Not Correlate with Telomere Length and Radiation Sensitivity in Human Cancer Cell Lines

Mammalian telomeres are transcribed into long non-coding telomeric repeat-containing RNA (TERRA) molecules that seem to play a role in the maintenance of telomere stability. In human cells, CpG-island promoters drive TERRA transcription and are regulated by methylation. It was suggested that the amo...

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Detalles Bibliográficos
Autores principales: Smirnova, Alexandra, Gamba, Riccardo, Khoriauli, Lela, Vitelli, Valerio, Nergadze, Solomon G., Giulotto, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650684/
https://www.ncbi.nlm.nih.gov/pubmed/23717814
http://dx.doi.org/10.3389/fonc.2013.00115