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Lrp5 and Lrp6 Exert Overlapping Functions in Osteoblasts during Postnatal Bone Acquisition

The canonical Wnt signaling pathway is critical for skeletal development and maintenance, but the precise roles of the individual Wnt co-receptors, Lrp5 and Lrp6, that enable Wnt signals to be transmitted in osteoblasts remain controversial. In these studies, we used Cre-loxP recombination, in which...

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Detalles Bibliográficos
Autores principales: Riddle, Ryan C., Diegel, Cassandra R., Leslie, Julie M., Van Koevering, Kyle K., Faugere, Marie-Claude, Clemens, Thomas L., Williams, Bart O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651091/
https://www.ncbi.nlm.nih.gov/pubmed/23675479
http://dx.doi.org/10.1371/journal.pone.0063323