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Expression Analysis of Lrrk1, Lrrk2 and Lrrk2 Splice Variants in Mice
Missense mutations in the leucine-rich repeat kinase 2 gene (LRRK2) are linked to autosomal dominant forms of Parkinson’s disease (PD). In order to get insights into the physiological role of Lrrk2, we examined the distribution of Lrrk2 mRNA and different splice variants in the developing murine emb...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651128/ https://www.ncbi.nlm.nih.gov/pubmed/23675505 http://dx.doi.org/10.1371/journal.pone.0063778 |