Expression Analysis of Lrrk1, Lrrk2 and Lrrk2 Splice Variants in Mice

Missense mutations in the leucine-rich repeat kinase 2 gene (LRRK2) are linked to autosomal dominant forms of Parkinson’s disease (PD). In order to get insights into the physiological role of Lrrk2, we examined the distribution of Lrrk2 mRNA and different splice variants in the developing murine emb...

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Detalles Bibliográficos
Autores principales: Giesert, Florian, Hofmann, Andreas, Bürger, Alexander, Zerle, Julia, Kloos, Karina, Hafen, Ulrich, Ernst, Luise, Zhang, Jingzhong, Vogt-Weisenhorn, Daniela Maria, Wurst, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651128/
https://www.ncbi.nlm.nih.gov/pubmed/23675505
http://dx.doi.org/10.1371/journal.pone.0063778

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