Mucosal and Systemic Immune Responses to Mycobacterium tuberculosis Antigen 85A following Its Co-Delivery with CpG, MPLA or LTB to the Lungs in Mice

Pulmonary vaccination is a promising route for immunization against tuberculosis because the lung is the natural site of infection with Mycobacterium tuberculosis. Yet, adjuvants with a suitable safety profile need to be found to enhance mucosal immunity to recombinant antigens. The aim of this stud...

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Detalles Bibliográficos
Autores principales: Todoroff, Julie, Lemaire, Muriel M., Fillee, Catherine, Jurion, Fabienne, Renauld, Jean-Christophe, Huygen, Kris, Vanbever, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651129/
https://www.ncbi.nlm.nih.gov/pubmed/23675482
http://dx.doi.org/10.1371/journal.pone.0063344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651129/
https://www.ncbi.nlm.nih.gov/pubmed/23675482
http://dx.doi.org/10.1371/journal.pone.0063344

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