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Retinal Pigmented Epithelial Cells Cytotoxicity and Apoptosis through Activation of the Mitochondrial Intrinsic Pathway: Role Of Indocyanine Green, Brilliant Blue and Implications for Chromovitrectomy

PURPOSE: To investigate the in vitro effect of four vital dyes on toxicity and apoptosis in a human retinal pigment epithelial (RPE) cell line. METHODS: ARPE-19 cells were exposed to brilliant blue (BriB), methyl blue (MetB), acid violet (AcV) and indocyanine green (ICG). Balanced salt solution was...

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Detalles Bibliográficos
Autores principales: Penha, Fernando M., Pons, Marianne, Costa, Elaine Fiod, Barros, Nilana Meza Tenório, Rodrigues, Eduardo B., Cardoso, Emmerson Badaró, Dib, Eduardo, Maia, Mauricio, Marin-Castaño, Maria E., Farah, Michel Eid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651137/
https://www.ncbi.nlm.nih.gov/pubmed/23675521
http://dx.doi.org/10.1371/journal.pone.0064094