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Actin Microfilament Mediates Osteoblast Cbfa1 Responsiveness to BMP2 under Simulated Microgravity

Microgravity decreases osteoblastic activity, induces actin microfilament disruption and inhibits the responsiveness of osteoblast to cytokines, but the mechanisms remains enigmatic. The F-actin cytoskeleton has previously been implicated in manifold changes of cell shape, function and signaling obs...

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Detalles Bibliográficos
Autores principales: Dai, Zhongquan, Wu, Feng, Chen, Jian, Xu, Hongjie, Wang, Honghui, Guo, Feima, Tan, Yingjun, Ding, Bai, Wang, Jinfu, Wan, Yumin, Li, Yinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651164/
https://www.ncbi.nlm.nih.gov/pubmed/23675497
http://dx.doi.org/10.1371/journal.pone.0063661